Sail E0 Webinar
Question
On sampling a population, the frequency of homozygous recessive genotype (aa) is 36%. Calculate the following:
i) The frequency of dominant allele
ii) The frequency of dominant homozygous genotype
iii) The frequency of heterozygous genotype
Options:
A .  i - 0.6, ii - 0.12, iii - 0.36
B .  i - 0.4, ii - 0. 16, iii - 0.48
C .  i - 0.4, ii - 0.9, iii - 0.54
D .  Data insufficient to calculate
Answer: Option B
:
B
According to Hardy-Weinberg equation,
p2+2pq+q2=1andp+q=1
Assuming that ‘p’ is the frequency of occurrence of the dominant allele ‘A’ and ‘q’ is the frequency of occurrence of the recessive allele ‘a’, we could say that the frequency of occurrence of the genotype aa=36%
q×q=36
q2=0.36
q=0.36
q=0.6
Therefore the frequency of recessive allele a = 0.6
Applying the equation p+q = 1
p=1q
p=10.6=0.4
Therefore, the frequency of dominant allele A = 0.4
The frequency of the homozygous genotype (AA)=p2
p2=(0.4×0.4)=0.16
The frequency of the heterozygous genotype (Aa)=2pq
2pq=2×0.4×0.6=0.48

Was this answer helpful ?
Next Question

Submit Solution

Your email address will not be published. Required fields are marked *

Latest Videos

Latest Test Papers