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MCQs

Total Questions : 16 | Page 2 of 2 pages
Question 11. Before they can react, many molecules need to be destabilized. This state is typically achieved through
  1.    changing the three-dimensional shape of the molecule
  2.    the input of a small amount of activation energy
  3.    oxidizing the molecules by removing electrons
  4.    changing the reaction from a biosynthetic to a catabolic pathway
 Discuss Question
Answer: Option B. -> the input of a small amount of activation energy
Question 12. Which of the common features are shared between serine and aspartate proteases?
  1.    Both use a base to activate the nucleophile
  2.    All of these
  3.    Both show specificity for certain amino acid sequences
  4.    Both require water to complete the catalytic cycle
 Discuss Question
Answer: Option B. -> All of these
Question 13. Common feature in all serine proteases is a
  1.    single reactive serine residue
  2.    hydrophobic specificity pocket
  3.    cluster of reactive serine residues
  4.    hydrophilic specificity pocket
 Discuss Question
Answer: Option A. -> single reactive serine residue
Question 14. The cleavage specificity of trypsin and chymotrypsin depend in part on the
  1.    presence of a low-barrier hydrogen bond in the active site or specificity pocket
  2.    proximity of Ser 195 to the active site or specificity pocket
  3.    absence of water in the active site
  4.    size, shape, and charge of the active site or specificity pocket
 Discuss Question
Answer: Option D. -> size, shape, and charge of the active site or specificity pocket
Question 15. The E.coli pyruvic acid dehydrogenase complex is reported to
  1.    decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
  2.    Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
  3.    Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
  4.    retard the reduction of pyruvic acid to acetyl Co A and CO2
 Discuss Question
Answer: Option C. -> Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
Question 16. How is the enzyme COX-1 important in human health?
  1.    It is a chemical derivative of aspirin
  2.    It is critical for the biosynthesis of DNA
  3.    It catalyzes the production of hormones that maintain the stomach lining
  4.    It helps to transport carbon dioxide in the blood
 Discuss Question
Answer: Option C. -> It catalyzes the production of hormones that maintain the stomach lining

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