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MCQs

Total Questions : 105 | Page 2 of 11 pages
Question 11. Which category of enzymes belongs to class two in the international classification?
  1.    Hydrolases
  2.    Ligases
  3.    Transferases
  4.    Isomerase
 Discuss Question
Answer: Option C. -> Transferases
Answer: (c).Transferases
Question 12. The Woolf-Augusteinsson-Hofstee plot of ν versus ν/[S] and the Eadie-Scatchard plot of ν/[S] versus ν do not involve reciprocals of ν therefore are considered to be more reliable when the error in v is
  1.    non-significant
  2.    significant
  3.    nothing to do with the reliability
  4.    non significant in selected cases
 Discuss Question
Answer: Option B. -> significant
Answer: (b).significant
Question 13. The reciprocal equation for non competitive inhibition can be arranged to the equation for the
  1.    Dixon plot
  2.    Woolf-Augusteinsson-Hofstee plot
  3.    Eadie-Scatchard plot
  4.    Hanes-Woolf plot
 Discuss Question
Answer: Option A. -> Dixon plot
Answer: (a).Dixon plot
Question 14. Which of the following statements is true for enzymatically catalyzed reaction?
  1.    The activation energy of the reaction is lowered so that a larger proportion of the substrate qualifies to overcome it
  2.    Additional substrate molecules are energized to overcome the activation energy of the reaction
  3.    The activation energy of the reaction is increased, thus decreasing the likelihood that any substrate molecules will overcome it
  4.    The activation energy of the reaction is lowered so that a fewer substrate molecules can overcome it
 Discuss Question
Answer: Option A. -> The activation energy of the reaction is lowered so that a larger proportion of the substrate qualifies to overcome it
Answer: (a).The activation energy of the reaction is lowered so that a larger proportion of the substrate qualifies to overcome it
Question 15. The relationship between Keq, Km and Vmax is known as
  1.    Haldane equation
  2.    Michaelis Menten equation
  3.    Numerical solution approach
  4.    Gibbs-Helmholtz equation
 Discuss Question
Answer: Option A. -> Haldane equation
Answer: (a).Haldane equation
Question 16. In competitive inhibition a factor is obtained from the measurement of
  1.    Vmax
  2.    KM
  3.    Y-intercept in Lineweaver-Burk Plot
  4.    None of these
 Discuss Question
Answer: Option B. -> KM
Answer: (b).KM
Question 17. The conformational change in an enzyme after the substrate is bound that allows the chemical reaction to proceed, can be explained by
  1.    induced fit
  2.    transition
  3.    fit and fine
  4.    Pasteur
 Discuss Question
Answer: Option A. -> induced fit
Answer: (a).induced fit
Question 18. Which of these proteases is not a cysteine active site protease?
  1.    Calpain
  2.    Cathepsin D
  3.    Papain
  4.    None of the above
 Discuss Question
Answer: Option B. -> Cathepsin D
Answer: (b).Cathepsin D
Question 19. Given an enzyme with a Km = 10m M and Vmax = 100 m mol/min. If [S] = 100 m M, which of the following will be true?
  1.    A 10 fold increase in Vmax would increase velocity 10 fold y
  2.    A 10 fold decrease in Km would increase velocity
  3.    Both (a) and (b)
  4.    A 10 fold increase in Vmax would decrease velocity 20 fold
 Discuss Question
Answer: Option A. -> A 10 fold increase in Vmax would increase velocity 10 fold y
Answer: (a).A 10 fold increase in Vmax would increase velocity 10 fold y
Question 20. The active site of an enzyme remains
  1.    at the center of globular proteins
  2.    rigid and does not change shape
  3.    complementary to the rest of the molecule
  4.    none of the above
 Discuss Question
Answer: Option D. -> none of the above
Answer: (d).none of the above

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