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MCQs

Total Questions : 105 | Page 10 of 11 pages
Question 91. A noncompetitive inhibitor of an enzyme-catalyzed reaction
  1.    increases KM and increases Vmax
  2.    increases KM and reduces Vmax
  3.    reduces KM and increases Vmax
  4.    reduces KM and reduces Vmax
 Discuss Question
Answer: Option B. -> increases KM and reduces Vmax
Answer: (b).increases KM and reduces Vmax
Question 92. An allosteric inhibitor of an enzyme usually
  1.    participates in feedback regulation
  2.    denatures the enzyme
  3.    is a hydrophobic compound
  4.    causes the enzyme to work faster
 Discuss Question
Answer: Option A. -> participates in feedback regulation
Answer: (a).participates in feedback regulation
Question 93. A classical uncompetitive inhibitor is a compound that binds
  1.    reversibly to the enzyme substrate complex yielding an inactive ESI complex
  2.    irreversibly to the enzyme substrate complex yielding an inactive ESI complex
  3.    reversibly to the enzyme substrate complex yielding an active ESI complex
  4.    irreversibly to the enzyme substrate complex yielding an active ESI complex
 Discuss Question
Answer: Option A. -> reversibly to the enzyme substrate complex yielding an inactive ESI complex
Answer: (a).reversibly to the enzyme substrate complex yielding an inactive ESI complex
Question 94. Which of the following activity is possible by transferases?
  1.    Transfer of methyl groups
  2.    Transfer of glycosyl group
  3.    Both (a) and (b)
  4.    None of these
 Discuss Question
Answer: Option C. -> Both (a) and (b)
Answer: (c).Both (a) and (b)
Question 95. Which graphical method is used to determine an enzyme degree of cooperativity?
  1.    Hill plot
  2.    Koshland curve
  3.    Michaelis-Menten hyperbola
  4.    Can not be determined
 Discuss Question
Answer: Option A. -> Hill plot
Answer: (a).Hill plot
Question 96. Which of the following common drugs is not a specific enzyme inhibitor?
  1.    Iodine
  2.    Methotrexate
  3.    Sulfbnilamide
  4.    Penicillin
 Discuss Question
Answer: Option A. -> Iodine
Answer: (a).Iodine
Question 97. Non-competitive inhibitor of an enzyme catalyzed reaction
  1.    decreases Vmax
  2.    binds to Michaelis complex (ES)
  3.    both (a) and (b)
  4.    can actually increase reaction velocity in rare cases
 Discuss Question
Answer: Option C. -> both (a) and (b)
Answer: (c).both (a) and (b)
Question 98. Which of the following statements is not true?
  1.    Enzymes are proteins that bind to specific substrates and increase the velocity of reactions involving those substrates
  2.    Enzymes function by overcoming the activation energy barrier of a reaction
  3.    Enzymes make thermodynamically favorable reactions to proceed; they cannot make unfavorable reactions to occur
  4.    Enzymes only function when they are in intact cells
 Discuss Question
Answer: Option D. -> Enzymes only function when they are in intact cells
Answer: (d).Enzymes only function when they are in intact cells
Question 99. In a Lineweaver-Burk Plot, competitive inhibitor shows which of the following effect?
  1.    It moves the entire curve to right
  2.    It moves the entire curve to left
  3.    It changes the x-intercept
  4.    It has no effect on the slope
 Discuss Question
Answer: Option C. -> It changes the x-intercept
Answer: (c).It changes the x-intercept
Question 100. The enzyme inhibition can occur by
  1.    reversible inhibitors
  2.    irreversible inhibitors
  3.    Both (a) and (b)
  4.    None of these
 Discuss Question
Answer: Option C. -> Both (a) and (b)
Answer: (c).Both (a) and (b)

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