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MCQs

Total Questions : 121 | Page 2 of 13 pages
Question 11. The enzyme that catalyzes the splitting of PIP2 into two molecules of inositol triphosphate (IP3) and diacylglycerol in cell signaling, is
  1.    phosphokinase C
  2.    phospholipase C
  3.    phosphodiesterase C
  4.    lipokinase
 Discuss Question
Answer: Option B. -> phospholipase C
Answer: (b).phospholipase C
Question 12. Which of the following processes involve the combining of a message from one signaling molecule with that of another to either enhance or inhibit a cellular effect?
  1.    Signal transduction
  2.    Signal reception
  3.    Signal integration
  4.    Signal amplification
 Discuss Question
Answer: Option C. -> Signal integration
Answer: (c).Signal integration
Question 13. A cell is known to respond to a particular signaling molecule. Which of the following must be true of this cell?
  1.    It is in the heart muscle
  2.    It is also the site of production for the signaling molecule
  3.    It contains the receptor for the signaling molecule
  4.    It is incapable of signal transduction
 Discuss Question
Answer: Option C. -> It contains the receptor for the signaling molecule
Answer: (c).It contains the receptor for the signaling molecule
Question 14. The binding of ligands to many G-proteins linked receptors leads to shortlived
  1.    increase in the concentration of certain intracellular signaling molecules called second messenger
  2.    decrease in the concentration of certain intracellular signaling molecules called second messenger
  3.    increase in the concentration of certain extracellular signaling molecules called first messenger
  4.    decrease in the concentration of certain extracellular signaling molecules called first messenger
 Discuss Question
Answer: Option A. -> increase in the concentration of certain intracellular signaling molecules called second messenger
Answer: (a).increase in the concentration of certain intracellular signaling molecules called second messenger
Question 15. A signal cascade induced by adrenaline or thyroxine
  1.    must begin with receipt of the signal molecule by a surface receptor
  2.    involves the activation of a G protein
  3.    results in the activation of a sequence of enzymes needed for the cell effect
  4.    all of the above
 Discuss Question
Answer: Option D. -> all of the above
Answer: (d).all of the above
Question 16. Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it
  1.    changes the shape and thus the enzymatic activity of the proteins involved
  2.    makes the receptor more likely to capture the signaling, molecule
  3.    allows hydrophilic signaling molecules to cross the plasma membrane
  4.    None of the above
 Discuss Question
Answer: Option A. -> changes the shape and thus the enzymatic activity of the proteins involved
Answer: (a).changes the shape and thus the enzymatic activity of the proteins involved
Question 17. When a __________ reaches its __________ , there is a specific means of receiving it and acting on the message. This task is the responsibility of specialized proteins called __________ .
  1.    signaling molecule; receptor; G proteins
  2.    signaling molecule; target cell; G proteins
  3.    signaling molecule; target cell; receptors
  4.    kinase; receptor; proteases
 Discuss Question
Answer: Option C. -> signaling molecule; target cell; receptors
Answer: (c).signaling molecule; target cell; receptors
Question 18. Which of the following statements about G proteins is false?
  1.    They are involved in signal cascades
  2.    They bind to and are regulated by guanine nucleotides
  3.    They become activated when bound to GDP
  4.    They must be active before the cell can make needed cAMP
 Discuss Question
Answer: Option C. -> They become activated when bound to GDP
Answer: (c).They become activated when bound to GDP
Question 19. Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?
  1.    Because other body tissues use a different signaling molecule
  2.    Because nitric oxide cannot cross cell membranes and enter the blood
  3.    Because nitric oxide breaks down quickly and thus cannot travel far
  4.    None of the above
 Discuss Question
Answer: Option C. -> Because nitric oxide breaks down quickly and thus cannot travel far
Answer: (c).Because nitric oxide breaks down quickly and thus cannot travel far
Question 20. Which of the following comes under the category of cell surface receptor?
  1.    Enzyme linked receptors
  2.    Ion-channel linked receptors
  3.    G protein linked receptors
  4.    All of these
 Discuss Question
Answer: Option D. -> All of these
Answer: (d).All of these

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