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Total Questions : 92 | Page 7 of 10 pages
Question 61. Antibiotics are typically produced in fed batch reactors because
  1.    the precursors are often toxic to the cells
  2.    antibiotic yields are generally higher when cell growth slows
  3.    antibiotic yields are generally higher when cells enter the stationary phase
  4.    All of these
 Discuss Question
Answer: Option D. -> All of these
Question 62. Which of the following event occurs during third phase of growth of P chrysogenum?
  1.    All of these
  2.    Concentration of antibiotic increases in the medium
  3.    Autolysis of the medium starts
  4.    Slight rise in pH due to liberation of ammonia
 Discuss Question
Answer: Option A. -> All of these
Question 63. Inoculum preparation for the fermentation medium for penicillin takes place on
  1.    all of these
  2.    rice seeds
  3.    barley seeds
  4.    wheat seeds
 Discuss Question
Answer: Option C. -> barley seeds
Question 64. Which of the following changes occur during first phase of growth of Penicillium chrysogenum?
  1.    Ammonia is liberated in the medium
  2.    Growth of mycelia occurs
  3.    All of these
  4.    Lactic acid present in the corn steep liquor is utilized at the maximum rate
 Discuss Question
Answer: Option C. -> All of these
Question 65.  The yield of the antibiotic depends upon
  1.    pH of the medium
  2.    age of the inoculum
  3.    composition of the medium
  4.    all of these
 Discuss Question
Answer: Option D. -> all of these
Question 66.  Fermentation medium for oxytetracyclin (terramycin) consist of
  1.    CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
  2.    CSL, (NH4)2 SO4, sodium chloride and CaCO3
  3.    CSL, starch,(NH4)2 SO4, ammonium chloride and CaCO3
  4.    CSL,(NH4)2 SO4, ammonium chloride and CaCO3
 Discuss Question
Answer: Option A. -> CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
Question 67.  
During which phase of growth of Penicillium chrysogenum maximum antibiotic production takes place
  1.    during the first phase
  2.    during the second phase
  3.    during the third phase
  4.    same in all the phases
 Discuss Question
Answer: Option B. -> during the second phase
Question 68.  At normal pH, penicillin remains in
  1.    aqueous phase
  2.    solvent phase
  3.    both (a) and (b)
  4.    precipitates
 Discuss Question
Answer: Option A. -> aqueous phase
Question 69.  pH of the fermentation medium for chlorotetracyclins is
  1.    5-6
  2.    6-7
  3.    7-8
  4.    8-9
 Discuss Question
Answer: Option A. -> 5-6
Question 70.  Chlorotetracyclin is soluble in
  1.    organic solvents
  2.    water
  3.    ether
  4.    all of these
 Discuss Question
Answer: Option B. -> water

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