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MCQs

Total Questions : 204 | Page 19 of 21 pages
Question 181. The mode of action of polymyxin is to
  1.    inhibit DNA synthesis
  2.    inhibit protein synthesis
  3.    injury to the plasma membrane
  4.    inhibit folic acid synthesis
 Discuss Question
Answer: Option C. -> injury to the plasma membrane
Question 182. Which of the following drugs may show plasmid-mediated resistance?
  1.    Ampicillin
  2.    Methicillin
  3.    Nalidixic acid
  4.    Rifampicin
 Discuss Question
Answer: Option A. -> Ampicillin
Question 183. The third generation cephalosporin agents is
  1.    cephalothin
  2.    cefotaxime
  3.    cephalexin
  4.    cefoxitin
 Discuss Question
Answer: Option B. -> cefotaxime
Question 184. Which of the following may cause resistance to penicillin?
  1.    Alteration or lack of penicillin-binding proteins
  2.    Production of β-lactamases by bacteria
  3.    All of these
  4.    Impermeability of cell envelope
 Discuss Question
Answer: Option C. -> All of these
Question 185. The penicillin resistant to β-lactamases is
  1.    closacillin
  2.    carbenicillin
  3.    ampicillin
  4.    penicillin-G
 Discuss Question
Answer: Option A. -> closacillin
Question 186. The antibiotics not clinically useful for Pseudomonas aeruginosa infection is
  1.    aminoglycosides
  2.    trimethoprim-sulphamethoxazole
  3.    piperacillin
  4.    ceftazidime
 Discuss Question
Answer: Option B. -> trimethoprim-sulphamethoxazole
Question 187. With which of the following aminoglycosides interfere?
  1.    Cell wall synthesis
  2.    Cell membrane function
  3.    DNA function
  4.    Protein synthesis
 Discuss Question
Answer: Option D. -> Protein synthesis
Question 188. The scientist who first discovered the substance penicillin was
  1.    Paul Ehrlich
  2.    Joseph Lister
  3.    Alexander Fleming
  4.    none of these
 Discuss Question
Answer: Option C. -> Alexander Fleming
Question 189. Chelate forming peptide antibiotic are/is
  1.    vancomycin
  2.    sideromycins
  3.    both (a) and (b)
  4.    bleomycins
 Discuss Question
Answer: Option C. -> both (a) and (b)
Question 190. The larger the __________ , the better the chemotherapeutic agent.
  1.    selective toxicity
  2.    therapeutic dose
  3.    therapeutic index
  4.    spectrum
 Discuss Question
Answer: Option C. -> therapeutic index

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