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Question
Which organ is considered as “Graveyard of RBC” where most of them are destroyed by macrophages?
Options:
A .  Red bone marrow
B .  Spleen
C .  Kidney
D .  Intestine
Answer: Option B
:
B
Old RBCs are destroyed along with the pathogens by phagocytosis that is carried out by macrophages. Macrophages can be found in large numbers in the lymphatic system, especially the spleen. Thus, the spleen acts as a graveyard of RBCs.

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