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Question
Which of the following is untrue about Homology-Based Programs?
Options:
A .  They are based on the fact that exon structures and exon sequences of related species are less conserved
B .  This approach assumes that the database sequences are correct
C .  It is a reasonable assumption in light of the fact that many homologous sequences to be compared with are derived from cDNA or expressed sequence tags (ESTs) of the same species
D .  Potential coding frames in a query sequence are translated and used to align with closest protein homologs found in databases
Answer: Option A
Answer: (a).They are based on the fact that exon structures and exon sequences of related species are less conserved

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