Which of the following is not true about Juxtaglomerular apparatus ? Options: A . &nbspLies at the junction of distal tubule and against the afferent (efferent) arteriole B . &nbspArteriole walls have juxtaglomerular cells, enlarged smooth muscle cells, Have secretory granules containing renin, Act as mechanoreceptors C . &nbspMacula densa function as chemoreceptors (sense concentrations of (Na+,K+andCl−) and on sensing higher levels of these ions, release prostaglandins which suppress the granular cells from releasing renin. D . &nbspMesangial cells, Have phagocytic and contractile properties, Influence capillary filtration

Which of the following is not true about Juxtaglomerular apparatus ?

Question

Which of the following is not true about Juxtaglomerular apparatus ?

Options:

A . Lies at the junction of distal tubule and against the afferent (efferent) arteriole

B . Arteriole walls have juxtaglomerular cells, enlarged smooth muscle cells, Have secretory granules containing renin, Act as mechanoreceptors

C . Macula densa function as chemoreceptors (sense concentrations of (Na+,K+andCl−) and on sensing higher levels of these ions, release prostaglandins which suppress the granular cells from releasing renin.

D . Mesangial cells, Have phagocytic and contractile properties, Influence capillary filtration

Answer: Option C
:
C
The macula densa cells, sense lower levels of sodium chloride, and release certain prostaglandins, that are local hormones- i.e., signaling molecules like hormones, but which act locally. The prostaglandins trigger the granular cells to release renin and not suppress them.

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