Which of the following is incorrect about Purification of protein complexes foll

Question

Which of the following is incorrect about Purification of protein complexes followed by mass spectrometry?

Options:

A . Isolating protein complexes from cells allows identification of interactions between ensembles of proteins instead of just pairs

B . Systematic purification of complexes on a large scale is done by tagging hundreds of genes with an epitope

C . UnLike in the yeast-two-hybrid assay, this does not involve chimeric genes

D . Affinity purification based on the epitope will then extract all the proteins attached to the bait protein from cell lysates

Answer: Option C
Answer: (c).UnLike in the yeast-two-hybrid assay, this does not involve chimeric genes

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