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Question
Which of the following is a mismatch?
Options:
A .  Live R strain - Non-virulent
B .  Heat-killed R strain - Virulent
C .  Live S strain - Pathogenic
D .  Heat-killed S strain - Non-pathogenic
Answer: Option B
:
B
Griffith considered two different strains of the bacterium Streptococcus pneumoniae - S strain and R strain. The former is pathogenic/virulent and can cause the disease, while the latter is non-pathogenic/non-virulent and cannot cause the disease. Heat-killed S strain bacteria however, lose their virulence and become non-pathogenic. R strain bacteria in general, don’t need to be heat-killed as they are already non-pathogenic.

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