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Question
Which of the following does not describe local alignment?
Options:
A .  A local alignment aligns a substring of the query sequence to a substring of the target sequence
B .  A local alignment is defined by maximizing the alignment score, so that deleting a column from either end would reduce the score, and adding further columns at either end would also reduce the score
C .  Local alignments have terminal gaps
D .  The substrings to be examined may be all of one or both sequences; if all of both are included then the local alignment is also global
Answer: Option C
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