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Question
Self reactive antibodies are not found in significant concentration in normal serum because
Options:
A .  it is impossible to generate a self-reactive antibody
B .  self reactive B cells are killed by CD8 T cells
C .  B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide
D .  self reactive B cells switch to IgA which is all secreted and not present in serum
Answer: Option C
Answer: (c).B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide

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