At present, there are essentially two types of method of RNA structure predictio

Question

At present, there are essentially two types of method of RNA structure prediction. One is the minimum free energy approach and the Second one is a comparative approach.

Options:

A . True

B . False

C . May be True or False

D . Can't say

Answer: Option A
Answer: (a).True

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Question 1. Ab initio approach makes structural predictions based on ______....

Question 2. In ab initio approach, generally, when a base pairing is formed, the energy of the molecule is _________ because of attr....is _________ because of attractive interactions between the two strands.

Question 3. In ab initio methods, free energy can be calculated based on parameters empirically derived for small molecules.....

Question 4. The energy necessary to form individual base pairs is not quite affected by adjacent base pairs.....

Question 5. In dot matrix in ab initio methods, the diagonals _____________ to the main diagonal represent regions that can self hyb....to the main diagonal represent regions that can self hybridize.

Question 6. In dot matrix in ab initio methods, one way to reduce the noise in the matrix is to select an appropriate window size of....window size of a maximum number of contiguous base matches.

Question 7. In ab initio methods, a quantitative approach such as dynamic programming can be used to assemble a final structure with....used to assemble a final structure with optimal base-paired regions.

Question 8. In dynamic programming, in ab initio methods, Often ________ base pairing and energy terms of the base pairing _____ inc....of the base pairing _____ incorporated into the scoring process.

Question 9. In dynamic programming, in ab initio methods, the use of a dot plot can be effective in finding a ____ secondary structu....in finding a ____ secondary structure in a ________ molecule.

Question 10. The dynamic programming method produces ____ structure with _____ score.....

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