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MCQs

Total Questions : 189 | Page 13 of 19 pages
Question 121. Glucorticoid-responsive element is ______ promoter from ______ of mouse mammory tumour virus (MMTV).
  1.    inducible, short terminal repeat region
  2.    inducible, long terminal repeat region
  3.    constitutive, short terminal repeat region
  4.    constitutive, long terminal repeat region
 Discuss Question
Answer: Option B. -> inducible, long terminal repeat region
Answer: (b).inducible, long terminal repeat region
Question 122. There are a group of promoters from the genes for metallothioneins. These are a group of proteins rich in ______ residues.
  1.    cysteine
  2.    methionine
  3.    either cysteine or methionine
  4.    cysteine and methionine both
 Discuss Question
Answer: Option A. -> cysteine
Answer: (a).cysteine
Question 123. If the embryo is at one-cell stage then it is found in ____________
  1.    ovary
  2.    oviduct
  3.    uterus
  4.    either ovary or uterus
 Discuss Question
Answer: Option B. -> oviduct
Answer: (b).oviduct
Question 124. Embryonic stem cells are also used for generation of transgenic organisms. They are obtained from _______ of a developing ________
  1.    trophoectoderm, gastrula
  2.    trophoectoderm, blastula
  3.    inner cell mass, blastula
  4.    inner cell mass, gastrula
 Discuss Question
Answer: Option C. -> inner cell mass, blastula
Answer: (c).inner cell mass, blastula
Question 125. Embryonic stem cells (ES) are isolated and are injected again into the blastocoel of a developing embryo. The embryo which develops is entirely made up of these cells only.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 126. ES cells are used in order to ensure that insertion is done at the required chromosomal location and it is called as ____________
  1.    gene targeting
  2.    knocking out
  3.    knocking in
  4.    gene disruption
 Discuss Question
Answer: Option A. -> gene targeting
Answer: (a).gene targeting
Question 127. Integration events may be insertional involving _____ crossover or replacement involving _____ crossovers.
  1.    single, single
  2.    double, double
  3.    double, single
  4.    single, double
 Discuss Question
Answer: Option D. -> single, double
Answer: (d).single, double
Question 128. If a gene is inactivated by gene targeting then it is called as ____________
  1.    knock-in gene
  2.    knock-out gene
  3.    gene disruption
  4.    insertional inactivation
 Discuss Question
Answer: Option B. -> knock-out gene
Answer: (b).knock-out gene
Question 129. It is necessary to analyze the genome of transgenic cells to confirm that the site of integration is correct. This is carried out by southern blotting.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 130. The gene targeting approach produces individuals which are ______ for inactivation of the gene.
  1.    homozygous
  2.    heterozygous
  3.    either only homozygous or only heterozygous
  4.    both heterozygous and homozygous
 Discuss Question
Answer: Option B. -> heterozygous
Answer: (b).heterozygous

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