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Question
Which of the following is false in case of the database Pfam and its algorithm?
Options:
A .  Each motif or domain is represented by an HMM profile generated from the seed alignment of a number of conserved homologous proteins
B .  Since the probability scoring mechanism is more complex in HMM than in a profile-based approach the use of HMM yields further increases in sensitivity of the database matches
C .  Pfam-B only contains sequence families not covered in Pfam
D .  The functional annotation of motifs in Pfam-A is often related to that in UNIPROT
Answer: Option D
Answer: (d).The functional annotation of motifs in Pfam-A is often related to that in UNIPROT

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