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Question
In large doses, analgesics that work in the brain as antagonists to certain chemicals have caused psychological disturbances in patients, which may limit their potential to relieve severe pain.
Options:
A .  Which may limit their potential for relieving
B .  Which may limit such analgesics' potential to relieve
C .  An effect that may limit their potential to relieve
D .  An effect that may limit the potential of such analgesics for relieving
E .  No wonder that centuries after it happened, the Black Death is still a bestseller.
Answer: Option D
:
D
Option: (D)
In option A, which is modifying patients in place of psychological disturbances.
In option B, which is modifying patients in place of psychological disturbances.
We have to choose between Option C and D.
In option D, "thier" is ambiguous and could refer back to patients or anlalgesics thus making it an incorrect option.

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