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MCQs

Total Questions : 65 | Page 2 of 7 pages
Question 11. The RNA polymerases that transcribe bacterial DNA are
  1.    interchangable with DNA polymerases
  2.    multisubunit enzymes
  3.    highly glycosylated in their active forms
  4.    only active inside the cell
 Discuss Question
Answer: Option B. -> multisubunit enzymes
Question 12. What is a promoter?
  1.    None of these
  2.    A specific sequence of DNA to which RNA polymerase binds
  3.    A specific DNA sequence to which a restriction endonuclease binds
  4.    A specific sequence of DNA to which a catabolic repressor binds
 Discuss Question
Answer: Option B. -> A specific sequence of DNA to which RNA polymerase binds
Question 13. In both eukaryotes and prokaryotes, a promoter region that is rich in AT bases is called as
  1.    CATT
  2.    Shine Dalgarno region
  3.    SV40 region
  4.    TATA box
 Discuss Question
Answer: Option D. -> TATA box
Question 14. The function of the sigma factor of RNA polymerase is to
  1.    assure that transcription ends at the proper point
  2.    assure that transcription begins at the proper point
  3.    assure that translation begins at the proper point
  4.    assure that translation ends at the proper point
 Discuss Question
Answer: Option B. -> assure that transcription begins at the proper point
Question 15. Immediately after transcription
  1.    a methylated guanine cap is added to the 31 end of the transcript
  2.    a methylated guanine cap is added to the 51 end of the transcript
  3.    a poly adenylation signal is added
  4.    both (a) and (b)
 Discuss Question
Answer: Option B. -> a methylated guanine cap is added to the 51 end of the transcript
Question 16. Transcription factors are
  1.    CATT boxes
  2.    proteins which bind to DNA and regulate transcription
  3.    promoters
  4.    TATA boxes
 Discuss Question
Answer: Option B. -> proteins which bind to DNA and regulate transcription
Question 17. The closed complex at bacterial promoters is
  1.    bound more tightly when repressors are present
  2.    not affected by promoter mutations
  3.    not affected by activator proteins
  4.    in equilibrium with free RNA polymerase and the promoter
 Discuss Question
Answer: Option D. -> in equilibrium with free RNA polymerase and the promoter
Question 18. Most transcripts of protein coding genes are cleaved
  1.    at the 5' end immediately after a poly adenylation signal
  2.    at the 5' end immediately before a poly adenylation signal
  3.    at the 3' end just before a poly adenylation signal
  4.    at the 3' end just after a poly adenylation signal
 Discuss Question
Answer: Option D. -> at the 3' end just after a poly adenylation signal
Question 19. RNA is synthesized on a DNA template in a process called __________ , which utilizes the enzyme __________
  1.    replication, DNA polymerase
  2.    transcription, RNA polymerase
  3.    transcription, DNA polymerase
  4.    translation, RNA polymerase
 Discuss Question
Answer: Option B. -> transcription, RNA polymerase
Question 20. The major function of RNA polymerase's sigma factor is
  1.    recognition of the translational start sequence
  2.    recognition of the transcriptional start sequence
  3.    recognition of the translational stop sequence
  4.    recognition of the transcriptional stop sequence
 Discuss Question
Answer: Option B. -> recognition of the transcriptional start sequence

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