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MCQs

Total Questions : 90 | Page 3 of 9 pages
Question 21. At present, there are essentially two types of method of RNA structure prediction. One is the minimum free energy approach and the Second one is a comparative approach.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 22. Ab initio approach makes structural predictions based on ______
  1.    a single RNA sequence
  2.    comparing RNA sequences
  3.    evolutionary basis
  4.    pure phylogenetics
 Discuss Question
Answer: Option A. -> a single RNA sequence
Answer: (a).a single RNA sequence
Question 23. In ab initio approach, generally, when a base pairing is formed, the energy of the molecule is _________ because of attractive interactions between the two strands.
  1.    lowered
  2.    increased
  3.    multiplied
  4.    kept stable
 Discuss Question
Answer: Option A. -> lowered
Answer: (a).lowered
Question 24. In ab initio methods, free energy can be calculated based on parameters empirically derived for small molecules.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 25. The energy necessary to form individual base pairs is not quite affected by adjacent base pairs.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 26. In dot matrix in ab initio methods, the diagonals _____________ to the main diagonal represent regions that can self hybridize.
  1.    parallel
  2.    cutting in random fashion
  3.    perpendicular
  4.    adjacent parallel
 Discuss Question
Answer: Option C. -> perpendicular
Answer: (c).perpendicular
Question 27. In dot matrix in ab initio methods, one way to reduce the noise in the matrix is to select an appropriate window size of a maximum number of contiguous base matches.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 28. In ab initio methods, a quantitative approach such as dynamic programming can be used to assemble a final structure with optimal base-paired regions.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 29. In dynamic programming, in ab initio methods, Often ________ base pairing and energy terms of the base pairing _____ incorporated into the scoring process.
  1.    G-C, are
  2.    G–U, are not
  3.    G–U, are also
  4.    G-C, are not
 Discuss Question
Answer: Option C. -> G–U, are also
Answer: (c).G–U, are also
Question 30. In dynamic programming, in ab initio methods, the use of a dot plot can be effective in finding a ____ secondary structure in a ________ molecule.
  1.    multiple, large
  2.    single, large
  3.    single, small
  4.    multiple, small
 Discuss Question
Answer: Option C. -> single, small
Answer: (c).single, small

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