Questions and answers for exam Preparation

MCQs

Total Questions : 90 | Page 1 of 9 pages

Question 1. In comparative approach to RNA structure prediction, algorithms that do not use pre-alignment, align multiple input sequences and infers a consensus structure.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 2. In comparative approach to RNA structure prediction, Dynalign is a ________ program.

Windows based
Fedora
UNIX
iOS based

Discuss Question

Answer: Option C. -> UNIX
Answer: (c).UNIX

Question 3. In comparative approach to RNA structure prediction, Foldalign is a web-based only program for RNA alignment

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 4. In comparative approach to RNA structure prediction, the Foldalign program doesn’t use the covariation information.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 5. In comparative approach to RNA structure prediction, in Dynalign program–by comparing _________ from each sequence, a ______ structure common to both sequences is selected that serves as the basis for sequence alignment.

multiple alternative structures, lowest energy
single structure, lowest energy
single structure, highest energy
multiple alternative structures, highest energy

Discuss Question

Answer: Option A. -> multiple alternative structures, lowest energy
Answer: (a).multiple alternative structures, lowest energy

Question 6. Which of the following is incorrect about the prediction of RNA secondary structure?

Every base is first compared to every other base by a type of analysis very similar to the dot matrix analysis
A row of matches in the RNA matrix indicates a succession of complementary nucleotides that can potentially form a double-stranded region
A row of matches in the RNA matrix indicates a failure of complementary nucleotides that can potentially form a double-stranded region
The sequence is listed across the top and down the side of the page, and G/C, A/U, and G/U base pairs are scored

Discuss Question

Answer: Option C. -> A row of matches in the RNA matrix indicates a failure of complementary nucleotides that can potentially form a double-stranded region
Answer: (c).A row of matches in the RNA matrix indicates a failure of complementary nucleotides that can potentially form a double-stranded region

Question 7. The sequence is listed down the first column of base comparisons’ table and free energy calculations’ table in the 5’→3’ orientation.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 8. Through a single scoring matrix, evaluation of all the different possible configurations is done.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 9. The increase depends on the type and length of loop that is introduced by the non-complementary base pair, whether internal loop, bulge loop, or hairpin loop.