Bioinformatics

RNA STRUCTURE PREDICTION MCQs

Total Questions : 90

Page 1 of 9 pages
Question 1. In comparative approach to RNA structure prediction, algorithms that do not use pre-alignment, align multiple input sequences and infers a consensus structure.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer is Option A. -> True
Answer: (a).True
Question 2. In comparative approach to RNA structure prediction, Dynalign is a ________ program.
  1.    Windows based
  2.    Fedora
  3.    UNIX
  4.    iOS based
 Discuss Question
Answer is Option C. -> UNIX
Answer: (c).UNIX
Question 3. In comparative approach to RNA structure prediction, Foldalign is a web-based only program for RNA alignment
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer is Option B. -> False
Answer: (b).False
Question 4. In comparative approach to RNA structure prediction, the Foldalign program doesn’t use the covariation information.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer is Option B. -> False
Answer: (b).False
Question 5. In comparative approach to RNA structure prediction, in Dynalign program–by comparing _________ from each sequence, a ______ structure common to both sequences is selected that serves as the basis for sequence alignment.
  1.    multiple alternative structures, lowest energy
  2.    single structure, lowest energy
  3.    single structure, highest energy
  4.    multiple alternative structures, highest energy
 Discuss Question
Answer is Option A. -> multiple alternative structures, lowest energy
Answer: (a).multiple alternative structures, lowest energy
Question 6. Which of the following is incorrect about the prediction of RNA secondary structure?
  1.    Every base is first compared to every other base by a type of analysis very similar to the dot matrix analysis
  2.    A row of matches in the RNA matrix indicates a succession of complementary nucleotides that can potentially form a double-stranded region
  3.    A row of matches in the RNA matrix indicates a failure of complementary nucleotides that can potentially form a double-stranded region
  4.    The sequence is listed across the top and down the side of the page, and G/C, A/U, and G/U base pairs are scored
 Discuss Question
Answer is Option C. -> A row of matches in the RNA matrix indicates a failure of complementary nucleotides that can potentially form a double-stranded region
Answer: (c).A row of matches in the RNA matrix indicates a failure of complementary nucleotides that can potentially form a double-stranded region
Question 7. The sequence is listed down the first column of base comparisons’ table and free energy calculations’ table in the 5’→3’ orientation.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer is Option A. -> True
Answer: (a).True
Question 8. Through a single scoring matrix, evaluation of all the different possible configurations is done.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer is Option B. -> False
Answer: (b).False
Question 9. The increase depends on the type and length of loop that is introduced by the non-complementary base pair, whether internal loop, bulge loop, or hairpin loop.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer is Option A. -> True
Answer: (a).True
Question 10. The object is to find a diagonal row of matches that goes from upper left to lower right.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer is Option B. -> False
Answer: (b).False