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MCQs

Total Questions : 369 | Page 1 of 37 pages
Question 1. 30 nm wide helix with five or six nucleosomes per helix is known as
  1.    solenoid
  2.    halonoid
  3.    kinoplast
  4.    none of these
 Discuss Question
Answer: Option A. -> solenoid
Answer: (a).solenoid
Question 2. DNA polymerases I also has
  1.    5'-3' exonuclease activity
  2.    3'-5'exonuclease activity
  3.    both (a) and (b)
  4.    5'-3' endonuclease activity
 Discuss Question
Answer: Option B. -> 3'-5'exonuclease activity
Answer: (b).3'-5'exonuclease activity
Question 3. Which of the following is used to determine the appropriate stringency (Wallace rule)?
  1.    Tm = 2 x (No.of G:C base pair) + 4 x (No.of A:T base pair)
  2.    Tm = 4 x (No.of A:T base pair) + 2 x (No.of G:C base pair)
  3.    Tm = 4 x (No.of G:C base pair) + 2 x (No.of A:T base pair)
  4.    Tm = 69.3° + 0.41 (%)G+C -650/1
 Discuss Question
Answer: Option C. -> Tm = 4 x (No.of G:C base pair) + 2 x (No.of A:T base pair)
Answer: (c).Tm = 4 x (No.of G:C base pair) + 2 x (No.of A:T base pair)
Question 4. Without telomerase, what would happen to the ends of chromosomes after each round of replication?
  1.    Chromosomes would become progressively shorter
  2.    Nothing would happen
  3.    Chromosomes would get longer
  4.    none of the above
 Discuss Question
Answer: Option A. -> Chromosomes would become progressively shorter
Answer: (a).Chromosomes would become progressively shorter
Question 5. One hypothesis of DNA replication suggested that the parental DNA molecules are broken into fragments. Both strands of DNA in each of the daughter molecules are made up of an assortment of parental and new DNA. This statement refers to which hypothesis?
  1.    Conservative theory
  2.    Dispersive theory
  3.    Semi-conservative theory
  4.    Evolutionary theory
 Discuss Question
Answer: Option B. -> Dispersive theory
Answer: (b).Dispersive theory
Question 6. What is the approximate percentage of repetitive DNA sequences in human DNA?
  1.    10 to 20%
  2.    20 to 30%
  3.    30 to 40%
  4.    40 to 50%
 Discuss Question
Answer: Option B. -> 20 to 30%
Answer: (b).20 to 30%
Question 7. The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?
  1.    AZT (zidovudine) is too expensive to be taken in effective doses
  2.    The RNase H domain of p66 causes error prone synthesis
  3.    It lacks a proofreading exonuclease
  4.    It has low affinity for the correct dNTP's
 Discuss Question
Answer: Option C. -> It lacks a proofreading exonuclease
Answer: (c).It lacks a proofreading exonuclease
Question 8. The packing ratio of nucleosomes is about
  1.    6
  2.    8
  3.    7
  4.    9
 Discuss Question
Answer: Option C. -> 7
Answer: (c).7
Question 9. The replication of a linear DNA molecule in a eukaryotic chromosome creates a problem which is reported to be sorted out by
  1.    using enzyme called telomerase
  2.    shortening of the double stranded replicated portion
  3.    using RNA as a template
  4.    none of the above
 Discuss Question
Answer: Option A. -> using enzyme called telomerase
Answer: (a).using enzyme called telomerase
Question 10. After one replication in 15N, how many bands should be observed in a cesium chloride gradient?
  1.    One
  2.    Two
  3.    Three
  4.    A smear
 Discuss Question
Answer: Option A. -> One
Answer: (a).One

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