Questions and answers for exam Preparation

MCQs

Total Questions : 39 | Page 1 of 4 pages

Question 1. Drugs in patients with renal impairment have same pharmacokinetic profile as in a person without renal failure.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 2. The time period for which the plasma concentration of drug remains above minimum effective concentration is known as ______________

Onset of time
Onset of action
Duration of drug of action
Therapeutic range

Discuss Question

Answer: Option C. -> Duration of drug of action
Answer: (c).Duration of drug of action

Question 3. Haemodialysis is also known as extracorporeal dialysis.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 4. Which of the following will not be a factor governing the removal of substances through dialysis?

Molecular weight
Water solubility
Disintegration time
Protein binding

Discuss Question

Answer: Option C. -> Disintegration time
Answer: (c).Disintegration time

Question 5. Which kind of membrane is used in haemodialysis?

Artificial Semipermeable membrane
Permeable membrane
Natural semipermeable membrane of the peritoneal cavity
Artificial permeable membrane

Discuss Question

Answer: Option A. -> Artificial Semipermeable membrane
Answer: (a).Artificial Semipermeable membrane

Question 6. Which of the following is not a characteristic of the caternary compartment model?

It gives a visual representation of various rate processes in drug disposition
It shows how many rate constants are necessary
Compartments and parameters bear a relationship with physiologic functions
Useful in predicting drug

Discuss Question

Answer: Option C. -> Compartments and parameters bear a relationship with physiologic functions
Answer: (c).Compartments and parameters bear a relationship with physiologic functions

Question 7. In noncompartmental analysis, Mean residence time is equal to _____________

The area under the first moment curve/area under the zero moment curve
The area under the zero moment’s curve/area under the first moment curve
1 / Area under the first-moment curve
1/ Area under the zero moment curve

Discuss Question

Answer: Option A. -> The area under the first moment curve/area under the zero moment curve
Answer: (a).The area under the first moment curve/area under the zero moment curve

Question 8. Which model is also known as membrane permeation rate limited?

Physiologic model
Compartment model
Noncompartment model
Mammillary model

Discuss Question

Answer: Option A. -> Physiologic model
Answer: (a).Physiologic model

Question 9. Which of the following will be a disadvantage for the physiologic model?

Prediction of drug concentration in various body regions
Correlation of data in several animal species
Obtaining experimental data for each of the organs
The model gives an exact description of the drug concentration-time profile for any organ

Discuss Question

Answer: Option C. -> Obtaining experimental data for each of the organs
Answer: (c).Obtaining experimental data for each of the organs

Question 10. Which pharmacokinetic model is drawn on the basis of anatomic and physiologic data?