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MCQs

Total Questions : 107 | Page 9 of 11 pages
Question 81. The most stabilizing force for nucleic acids is
  1.    electrostatic bond
  2.    Van der Waals
  3.    conformational entropy
  4.    hydrogen bonds
 Discuss Question
Answer: Option B. -> Van der Waals
Question 82. Which of the following is a purine?
  1.    Cytosine
  2.    Uracil
  3.    Thymine
  4.    Adenine
 Discuss Question
Answer: Option D. -> Adenine
Question 83. Different DNA polymerases play distinct roles in DNA replication and repair in both prokaryotic and eukaryotic cells. All known DNA polymerases synthesize DNA only in the __________ by the addition of dNTPs to a performed primer strand of DNA.
  1.    negative direction
  2.    5' to 3' direction
  3.    3' to 5' direction
  4.    positive direction
 Discuss Question
Answer: Option B. -> 5' to 3' direction
Question 84. Which of the following amino acids can interact with the DNA or RNA nucleotide bases via hydrogen bonding?
  1.    Lys and Leu
  2.    Cys and Met
  3.    Asn and Gln
  4.    Ile and Val
 Discuss Question
Answer: Option C. -> Asn and Gln
Question 85. Reverse transcripase from HIV does not
  1.    has a 3'- 5' exonuclease activity
  2.    has a 5' to 3' polymerase activity
  3.    uses RNA as a template
  4.    requires a primer
 Discuss Question
Answer: Option A. -> has a 3'- 5' exonuclease activity
Question 86. The type II restriction endonucleases, bind to DNA sites
  1.    using H-bonds for specificity
  2.    that are usually palindromic
  3.    using non-sequence-dependent backbone interactions
  4.    All of these
 Discuss Question
Answer: Option D. -> All of these
Question 87. The enzyme that joins DNA cuts is called
  1.    reverse transcriptase
  2.    DNA phosphorylase
  3.    ligase
  4.    joinase
 Discuss Question
Answer: Option C. -> ligase
Question 88. Cleavage of DNA by EcoRI endonuclease results in the formation of
  1.    one 3'-OH end and one 5'-phosphate end
  2.    one 3'-OH end and two 5'-phosphate end
  3.    two 3'-OH ends and two 5'-phosphate ends
  4.    two 3'-phosphate ends and two 3'-OH ends
 Discuss Question
Answer: Option C. -> two 3'-OH ends and two 5'-phosphate ends
Question 89. Which of the following amino acids interact with the DNA or RNA backbone (i.e. phosphate)?
  1.    Cys and Met
  2.    Lys and Arg
  3.    Ile and Val
  4.    Leu and Ala
 Discuss Question
Answer: Option B. -> Lys and Arg
Question 90.  Because DNA is a highly charged polyanion, its stability to heat denaturation
  1.    does not depend on hydrophobic interactions
  2.    increases with increasing salt
  3.    is independent of G - C content
  4.    decreases with increasing salt
 Discuss Question
Answer: Option B. -> increases with increasing salt

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