Microbiology > Dna Sequencing

MUTATION AND REPAIR MCQs

Total Questions : 20

Page 1 of 2 pages
Question 1. Genetic variations are
  1.    influenced by the environment
  2.    not heritable
  3.    temporary
  4.    stable
 Discuss Question
Answer is Option D. -> stable
Question 2. Which of the following(s) is/are steps in excision repair mechanisms?
  1.    All of these
  2.    Excision
  3.    Ligation
  4.    Incision
 Discuss Question
Answer is Option A. -> All of these
Question 3. The whole-genome shotgun sequencing approach depends primarily on
  1.    sequencing the bacterial chromosome while it is still intact
  2.    rapidly sequencing thousands of small randomly cloned fragments
  3.    All of these
  4.    methodical sequencing a few large cloned fragments of DNA
 Discuss Question
Answer is Option B. -> rapidly sequencing thousands of small randomly cloned fragments
Question 4. The mutation which will not affect the length of a protein is,
  1.    missense mutation
  2.    all of these
  3.    nonsense mutation
  4.    frameshift mutation
 Discuss Question
Answer is Option A. -> missense mutation
Question 5. Changes in which of the following characterizes mutations?
  1.    Both (a) and (b)
  2.    Phenotype
  3.    None of these
  4.    Genotype
 Discuss Question
Answer is Option A. -> Both (a) and (b)
Question 6. Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?
  1.    New strands are lower in molecular size
  2.    New strands are methylated while old strands are not
  3.    New strands do not contain cytosine bases
  4.    Old strands are methylated while new strands are not
 Discuss Question
Answer is Option D. -> Old strands are methylated while new strands are not
Question 7. Which of the following mutations arise without exposure to external agents?
  1.    Induced mutations
  2.    Analogous mutations
  3.    Spontaneous mutations
  4.    None of these
 Discuss Question
Answer is Option C. -> Spontaneous mutations
Question 8. What was the first eukaryotic chromosome to be sequenced?
  1.    Yeast chromosome III
  2.    Yeast chromosome XI
  3.    Arabidopsis chromosome IV
  4.    None of these
 Discuss Question
Answer is Option A. -> Yeast chromosome III
Question 9. Which of the following bacterial genome was sequenced first?
  1.    S. thermophilus
  2.    S. pneumoniae
  3.    E. coli
  4.    H. influenzae
 Discuss Question
Answer is Option D. -> H. influenzae
Question 10. A nonsense mutation may result into
  1.    a large deletion within the reading frame of a gene
  2.    an abnormal elongation of a polypeptide
  3.    a premature termination of the synthesis of a polypeptide
  4.    modification of mRNA
 Discuss Question
Answer is Option C. -> a premature termination of the synthesis of a polypeptide