Questions and answers for exam Preparation

MCQs

Total Questions : 120 | Page 12 of 12 pages

Question 111. The _____ resolution genome map is the genomic DNA sequence that can be considered as a type of ______ map describing a genome at the single base-pair level.

highest, physical
lowest, physical
highest, cytological
lowest, cytological

Discuss Question

Answer: Option A. -> highest, physical
Answer: (a).highest, physical

Question 112. In DNA sequencing, the fluorescent traces of the DNA sequences are read by a computer program that assigns bases for each peak in a chromatogram.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 113. The shotgun approach _______ sequences clones from _____ of cloned DNA.

randomly, one end
randomly, both ends
specifically, both ends
specifically, one end

Discuss Question

Answer: Option B. -> randomly, both ends
Answer: (b).randomly, both ends

Question 114. The shotgun approach does not require knowledge of physical mapping of the clone fragments, but rather a robust computer assembly program to join the pieces of random fragments into a single, whole-genome sequence.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 115. Which of the following is untrue about DNA sequencing?

It is now routinely carried out using the Sanger method
This doesn’t make use of DNA polymerases
This involves the synthesis of DNA chains of varying length
The DNA synthesis is stopped by adding dideoxynucleotides

Discuss Question

Answer: Option B. -> This doesn’t make use of DNA polymerases
Answer: (b).This doesn’t make use of DNA polymerases

Question 116. Which of the following is untrue about Whole Genome Alignment?

This helps to reveal the presence of conserved functional elements
It doesn’t help to understand sequence conservation between genomes
It be accomplished through direct genome comparison or genome alignment
The alignment at the genome level is fundamentally no different from the basic sequence alignment

Discuss Question

Answer: Option B. -> It doesn’t help to understand sequence conservation between genomes
Answer: (b).It doesn’t help to understand sequence conservation between genomes

Question 117. Which of the following is untrue about comparative genomics?

It is comparison of whole genomes from different organisms
It includes comparison of gene number, gene location, and gene content from these genomes
It provides insights into the mechanism of genome evolution and gene transfer among genomes
It doesn’t help to reveal the extent of conservation among genomes

Discuss Question

Answer: Option C. -> It provides insights into the mechanism of genome evolution and gene transfer among genomes
Answer: (c).It provides insights into the mechanism of genome evolution and gene transfer among genomes

Question 118. Which of the following is untrue about LAGAN?

It stands for Limited Area Global Alignment of Nucleotides
It is a web-based program designed for pairwise alignment of small fragments of genomes only
It first finds anchors between two genomic sequences using an algorithm that identifies short, exactly matching words
Regions that have high density of words are selected as anchors

Discuss Question

Answer: Option B. -> It is a web-based program designed for pairwise alignment of small fragments of genomes only
Answer: (b).It is a web-based program designed for pairwise alignment of small fragments of genomes only

Question 119. Coregenes is a web-based program that determines a ________ set of genes based on comparison of ________ small genomes.