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MCQs

Total Questions : 120 | Page 11 of 12 pages
Question 101. Chloroplast localization signals are also located in the __________ terminus and are about 25 to 100 residues in length, containing very few _______ charged residues but many hydroxylated residues such as serine.
  1.    N, negatively
  2.    C, negatively
  3.    C, positively
  4.    N, positively
 Discuss Question
Answer: Option A. -> N, negatively
Answer: (a).N, negatively
Question 102. Which of the following is not one of the training sets in SignalP?
  1.    Prokaryotes
  2.    Eukaryotes
  3.    Gram-positive bacteria
  4.    Gram-negative bacteria
 Discuss Question
Answer: Option A. -> Prokaryotes
Answer: (a).Prokaryotes
Question 103. Which of the following is an incorrect statement about SignalP?
  1.    It only uses neural networks
  2.    It only uses HMMs
  3.    It is a web-based program that predicts subcellular localization signals
  4.    It uses both neural networks and HMMs
 Discuss Question
Answer: Option B. -> It only uses HMMs
Answer: (b).It only uses HMMs
Question 104. TargetP is a neural network-based program, similar to SignalP.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 105. Chloroplast localization signals consist of two adjacent signal peptides, one for targeting the proteins to the stromaportion of the chloroplast before being cleaved and the other for targeting the remaining portion of the proteins to the thylakoids.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 106. When the two domains are located in two different proteins, to preserve the same functionality, their close proximity and interaction have to be preserved as well.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 107. The justification behind Rosetta stone method is that when two domains are fused in a single protein, they have to be in _______ proximity to perform a common function.
  1.    distant
  2.    close
  3.    extremely distant
  4.    extremely close
 Discuss Question
Answer: Option D. -> extremely close
Answer: (d).extremely close
Question 108. In Predicting Interactions Based on Gene Neighbors if a certain gene linkage is found to be indeed conserved across divergent genomes, it can be used as a strong indicator of formation of an operon that encodes proteins that are functionally and even physically coupled.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 109. Which of the following is untrue regarding the STRING?
  1.    Search Tool for the Retrieval of Interacting Genes/Proteins
  2.    Functional associations include only the direct protein-protein interactions
  3.    It is based on combined evidence of gene linkage, gene fusion and phylogenetic profiles
  4.    It is a web server that predicts gene and protein functional associations
 Discuss Question
Answer: Option B. -> Functional associations include only the direct protein-protein interactions
Answer: (b).Functional associations include only the direct protein-protein interactions
Question 110. Which of the following is untrue regarding the predicting Interactions Based on Phylogenetic Information?
  1.    Proteins do not operate as a complex
  2.    This method detects the co-presence or co-absence of orthologs across a number of genomes
  3.    Protein interactions can be predicted using phylogenetic profiles
  4.    Phylogenetic profile are defined as patterns of gene pairs that are concurrently present or absent across genomes
 Discuss Question
Answer: Option A. -> Proteins do not operate as a complex
Answer: (a).Proteins do not operate as a complex

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