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MCQs

Total Questions : 34 | Page 1 of 4 pages
Question 1. Which of the following techniques was carried out by Nirenberg and Matthaei in 1961 to determine the first codon?
  1.    None of these
  2.    In vitro synthesis of a polypeptide using UUUUU
  3.    Labeled peptide binding to a ribosome
  4.    Mixed co-polymer mRNA synthesis
 Discuss Question
Answer: Option B. -> In vitro synthesis of a polypeptide using UUUUU
Question 2. Bacterial protein called catabolic activator protein (CAP) is an example of
  1.    negative control of gene expression
  2.    positive control of gene expression
  3.    second type of positive control of gene expression
  4.    None of these
 Discuss Question
Answer: Option C. -> second type of positive control of gene expression
Question 3. How many different codons are possible?
  1.    20
  2.    3
  3.    An infinite number
  4.    64
 Discuss Question
Answer: Option D. -> 64
Question 4. Which of the following has been used as an evidence that primitive life forms lacked both DNA and enzymes?
  1.    Advanced cells lack RNA
  2.    DNA and enzymes are only present in the most advanced cells
  3.    RNA can both code genetic information and act as a catalyst
  4.    All of these
 Discuss Question
Answer: Option C. -> RNA can both code genetic information and act as a catalyst
Question 5. The genetic code is
  1.    universal
  2.    species-specific
  3.    kingdom-specific
  4.    universal except for rare exceptions in mitochondria and some protozoa
 Discuss Question
Answer: Option D. -> universal except for rare exceptions in mitochondria and some protozoa
Question 6. Crick demonstrated that the genetic code involved three bases and suggested that the code was degenerated. What experimental technique Crick conducted to suggest genetic code degeneration?
  1.    Frameshift mutagenesis
  2.    Gel electrophoresis
  3.    Density gradient centrifugation
  4.    Restriction digests of the rII gene
 Discuss Question
Answer: Option A. -> Frameshift mutagenesis
Question 7. In some organelles in eukaryotes, the genetic code for some codons
  1.    None of these
  2.    are partially same
  3.    are same
  4.    differs from that used in prokaryotes
 Discuss Question
Answer: Option D. -> differs from that used in prokaryotes
Question 8. The codons which do not specify an amino acid are called
  1.    initiation code
  2.    termination code
  3.    propagation code
  4.    none of these
 Discuss Question
Answer: Option B. -> termination code
Question 9. The genetic code is degenerated. Which of the following codons represents the principle of degeneracy?
  1.    AUG and AUA
  2.    UUA and UUC
  3.    CAU and CAC
  4.    UAA and UAC
 Discuss Question
Answer: Option C. -> CAU and CAC
Question 10. Codon that specify the amino acids often differs in the
  1.    first base
  2.    none of these
  3.    third base
  4.    second base
 Discuss Question
Answer: Option C. -> third base

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