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MCQs

Total Questions : 15 | Page 1 of 2 pages
Question 1. Proofreading activity to maintain the fidelity of DNA synthesis
  1.    occurs in prokaryotes but not eukaryotes
  2.    occurs after the synthesis has been completed
  3.    is a function of the 3'-5' exonuclease activity of the DNA polymerases
  4.    requires the presence of an enzyme separate from the DNA polymerases
 Discuss Question
Answer: Option C. -> is a function of the 3'-5' exonuclease activity of the DNA polymerases
Question 2. The enzyme that catalyzes the synthesis of DNA is called
  1.    helicase
  2.    DNA gyrase
  3.    DNA polymerase
  4.    DNA ligase
 Discuss Question
Answer: Option C. -> DNA polymerase
Question 3. Which of the following possesses both 5'-3' and 3'-5' exonuclease activity?
  1.    DNA polymerase III
  2.    Kornberg enzyme
  3.    Taq DNA polymerase
  4.    None of these
 Discuss Question
Answer: Option B. -> Kornberg enzyme
Question 4. Both strands of DNA serve as templates concurrently in
  1.    replication
  2.    excision repair
  3.    mismatch repair
  4.    none of these
 Discuss Question
Answer: Option A. -> replication
Question 5. Which of the following repairs nicked DNA by forming a phosphodiester bond between adjacent nucleotides?
  1.    Helicase
  2.    DNA gyrase
  3.    DNA ligase
  4.    Topoisomerases
 Discuss Question
Answer: Option C. -> DNA ligase
Question 6. Which of the following statements on replication in E.coli is correct?
  1.    Always uses T7 DNA polymerase when infected by T7 phage
  2.    It occurs in bidirectional manner
  3.    It occurs in a unidirectional manner
  4.    Occurs only when λ phase has infected E. coli
 Discuss Question
Answer: Option B. -> It occurs in bidirectional manner
Question 7. DNA gyrase is inhibited by
  1.    cephalosporin
  2.    both (a) and (b)
  3.    nalidixic acid
  4.    tetracycline
 Discuss Question
Answer: Option C. -> nalidixic acid
Question 8. The replication of chromosomes by eukaryotes occurs in a relatively short period of time because
  1.    each chromosome contains multiple replicons
  2.    the eukaryotic replication machinery is 1000 times faster than the prokaryotes
  3.    the eukaryotes have more amount of DNA for replication
  4.    eukaryotic DNA is always single stranded
 Discuss Question
Answer: Option A. -> each chromosome contains multiple replicons
Question 9. During which of the following process a new copy of a DNA molecule is precisely synthesized?
  1.    Transcription
  2.    Translation
  3.    Replication
  4.    Trasformation
 Discuss Question
Answer: Option C. -> Replication
Question 10. In E.coli, which enzyme synthesizes the RNA primer for Okazaki fragments?
  1.    all of these
  2.    DnaG
  3.    DnaA
  4.    DnaC
 Discuss Question
Answer: Option B. -> DnaG

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