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Total Questions : 50 | Page 4 of 5 pages
Question 31. In heuristic methods, speed doesn’t vary with the size of database.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 32. An increase in sensitivity is associated with _______ in selectivity.
  1.    no specific change
  2.    increase
  3.    decrease
  4.    exponential increase
 Discuss Question
Answer: Option C. -> decrease
Answer: (c).decrease
Question 33. Which of the following is incorrect?
  1.    Smith–Waterman algorithm is the fastest
  2.    Smith–Waterman algorithm is comparatively slower method
  3.    To speedup up comparison, heuristic methods are used
  4.    Heuristic algorithms perform faster searches
 Discuss Question
Answer: Option A. -> Smith–Waterman algorithm is the fastest
Answer: (a).Smith–Waterman algorithm is the fastest
Question 34. Which of the following is incorrect the ‘word’ method?
  1.    Both BLAST and FASTA use a heuristic word method
  2.    Word method is used for fast pairwise sequence alignment in BLAST and FASTA
  3.    The basic assumption is that two related sequences must have at least one word in common
  4.    Two related sequences must have at zero word in common while assuming
 Discuss Question
Answer: Option D. -> Two related sequences must have at zero word in common while assuming
Answer: (d).Two related sequences must have at zero word in common while assuming
Question 35. Currently, there are two major heuristic algorithms for performing database searches: BLAST and FASTA.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 36. TBLASTX queries protein sequences to anucleotide sequence database with the sequences translated in all six reading frames.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 37. If one is looking for protein homologs encoded in newly sequenced genomes, one may use TBLASTN, which translates nucleotide database sequences in all six open reading frames.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 38. BLASTX uses protein sequences as queries to search against a protein sequence database.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 39. Which of the following is not a variant of BLAST?
  1.    BLASTN
  2.    BLASTP
  3.    BLASTX
  4.    TBLASTNX
 Discuss Question
Answer: Option D. -> TBLASTNX
Answer: (d).TBLASTNX
Question 40. Which of the following is not correct about BLAST?
  1.    The BLAST web server has been designed in such away as to simplify the task of program selection
  2.    The programs are organized based on the type of query sequences
  3.    The programs are organized based on the type of nucleotide sequences, or nucleotide sequence to be translated
  4.    BLAST is not based on heuristic searching methods
 Discuss Question
Answer: Option D. -> BLAST is not based on heuristic searching methods
Answer: (d).BLAST is not based on heuristic searching methods

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