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MCQs

Total Questions : 101 | Page 1 of 11 pages
Question 1. SH₂ domain specifically binds to _____________
  1.    GDP
  2.    Ca⁺²
  3.    Phosphorylated tyrosine residues
  4.    Phosphorylated serine residues
 Discuss Question
Answer: Option C. -> Phosphorylated tyrosine residues
Answer: (c).Phosphorylated tyrosine residues
Question 2. The enzyme activated by cyclic AMP, passing on the hormonal signal is ____________
  1.    Protein kinase B
  2.    Protein kinase A
  3.    Protein kinase C
  4.    G protein receptor kinase
 Discuss Question
Answer: Option B. -> Protein kinase A
Answer: (b).Protein kinase A
Question 3. Protein kinase ERK is activated by phosphorylation of ____________
  1.    Only Thr
  2.    Only Tyr
  3.    Both Thr and Tyr
  4.    Only Ser
 Discuss Question
Answer: Option C. -> Both Thr and Tyr
Answer: (c).Both Thr and Tyr
Question 4. CAMP and cGMP are derived from ____________
  1.    ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively
  2.    ATP and GTP by the actions of adenylate cyclase and gualnlate cyclase respectively
  3.    GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively
  4.    None of the mentioned
 Discuss Question
Answer: Option B. -> ATP and GTP by the actions of adenylate cyclase and gualnlate cyclase respectively
Answer: (b).ATP and GTP by the actions of adenylate cyclase and gualnlate cyclase respectively
Question 5. Which of the following is false about phosphorylation by IRS on serine residue?
  1.    It is an inhibitory phosphorylation
  2.    It is molecular mechanism for insulin resistance
  3.    It increases insulin levels
  4.    Target tissues fail to respond to circulating insulin
 Discuss Question
Answer: Option C. -> It increases insulin levels
Answer: (c).It increases insulin levels
Question 6. Ras protein is a ____________
  1.    G-protein switch
  2.    Small monomeric GTPase switch protein
  3.    Serine-threonine kinase
  4.    Tyrosine kinase
 Discuss Question
Answer: Option B. -> Small monomeric GTPase switch protein
Answer: (b).Small monomeric GTPase switch protein
Question 7. CGMP-dependent protein kinase is also called ____________
  1.    Protein kinase B
  2.    Protein kinase A
  3.    Protein kinase G
  4.    Protein kinase C
 Discuss Question
Answer: Option C. -> Protein kinase G
Answer: (c).Protein kinase G
Question 8. Which of the following is not responsible of producing diarrhea?
  1.    Elevation in [cGMP]
  2.    Increase in Cl⁻ secretion
  3.    Decrease in reabsorption of water by the intestinal epithelium
  4.    Decrease in Cl⁻ secretion
 Discuss Question
Answer: Option D. -> Decrease in Cl⁻ secretion
Answer: (d).Decrease in Cl⁻ secretion
Question 9. Activation of guanylyl cyclase produces ____________
  1.    Guanosine 3’, 5’-cyclic monophosphate
  2.    Guanosine 2’, 5’-cyclic monophosphate
  3.    Guanosine 4’, 5’-cyclic monophosphate
  4.    Guanosine 1’, 5’-cyclic monophosphate
 Discuss Question
Answer: Option A. -> Guanosine 3’, 5’-cyclic monophosphate
Answer: (a).Guanosine 3’, 5’-cyclic monophosphate
Question 10. Which of the following is a short-lived messenger that acts by stimulating a soluble guanylyl cyclase, raising [cGMP] and stimulating PKG?
  1.    NO
  2.    NO₂
  3.    NO₃⁻
  4.    N₂O
 Discuss Question
Answer: Option A. -> NO
Answer: (a).NO

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