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Total Questions : 119 | Page 3 of 12 pages
Question 21. An autoimmune disease is
  1.    AIDS
  2.    Measles
  3.    Lupus
  4.    Mumps
 Discuss Question
Answer: Option C. -> Lupus
Answer: (c).Lupus
Question 22. A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind
  1.    Leu or Ileu
  2.    His or Pro
  3.    Tyr or Phe
  4.    Ser or Thr
 Discuss Question
Answer: Option C. -> Tyr or Phe
Answer: (c).Tyr or Phe
Question 23. Retinoblastoma is due to a mutation in a
  1.    kinase
  2.    tumor supressor
  3.    cyclin
  4.    viral gene
 Discuss Question
Answer: Option B. -> tumor supressor
Answer: (b).tumor supressor
Question 24. If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced
  1.    alternative complement activation.
  2.    CD8 T cell-mediated cytotoxicity
  3.    macrophage activation to vesicular pathogens
  4.    IgG synthesis
 Discuss Question
Answer: Option A. -> alternative complement activation.
Answer: (a).alternative complement activation.
Question 25. Specific translocations are associated with
  1.    colon cancer
  2.    breast cancer
  3.    pancreatic cancer
  4.    some leukemias
 Discuss Question
Answer: Option D. -> some leukemias
Answer: (d).some leukemias
Question 26. The primary reason for AIDS, a deadly disease is that it
  1.    is caused by a virus
  2.    is caused by a bacterium
  3.    destroys key components of the body's internal defense system
  4.    causes a breakdown of the body's inflammatory response
 Discuss Question
Answer: Option C. -> destroys key components of the body's internal defense system
Answer: (c).destroys key components of the body's internal defense system
Question 27. DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a
  1.    knock-out mouse for RAG-1 and RAG-2
  2.    knock-out mouse for a thymus
  3.    nude mouse
  4.    recombinant mouse for CD3
 Discuss Question
Answer: Option C. -> nude mouse
Answer: (c).nude mouse
Question 28. To treat HIV infections using drugs, the major problem is that
  1.    the drugs that are good inhibitors cannot by synthesized
  2.    the drugs interfere with normal digestion
  3.    the virus particles with altered (mutant) proteases arise
  4.    the drugs are rapidly degraded
 Discuss Question
Answer: Option C. -> the virus particles with altered (mutant) proteases arise
Answer: (c).the virus particles with altered (mutant) proteases arise
Question 29. Which of the Rous sarcoma virus has a homologous cellular protein?
  1.    c-src
  2.    v-src
  3.    v-ha-src
  4.    v-ha-ras
 Discuss Question
Answer: Option A. -> c-src
Answer: (a).c-src
Question 30. Infants are most susceptible to bacterial infection due to low circulating levels of IgG
  1.    in utero (before birth)
  2.    at 0-3 months of age
  3.    at 3-12 months of age
  4.    at 12-24 months of age
 Discuss Question
Answer: Option C. -> at 3-12 months of age
Answer: (c).at 3-12 months of age

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