Match the disease in Column I with the respective symptoms in Column II: Column&

Question

Match the disease in Column I with the respective symptoms in Column II:

\begin{matrix} C o l u m n I & C o l u m n I I 1. R h e u m a t o i d a r t h r i t i s & (a) i m m u n e s y t e m a t t a c k s t h e j o i n t s 2. T y p e I d i a b e t e s & (b) i m m u n e s y s t e m a t t a c k s t h e m y e l i n s h e a t h 3. M u l t i p l e s c l e r o s i s & (c) i m m u n e s y s t e m d e s t r o y s p a n c r e a t i c c e l l s 4. M y a s t h e n i a g r a v i s & (d) i m m u n e s y s t e m d i s r u p t s m u s c l e c o n t r a c t i o n s (e) i m m u n e s y t e m d a m a g e s t h e a d r e n a l g l a n d \end{matrix}

Options:

A . 1 - a, 2 - c, 3 - b, 4 - d

B . 1 - a, 2 - c, 3 - d, 4 - b

C . 1 - b, 2 - c, 3 - d, 4 - a

D . 1 - d, 2 - c, 3 - b, 4 - a

Answer: Option A
:
A
Autoimmunity refers to the body’s development of intolerance to the antigens on its own cells i.e., there is an immune response to one’s own tissue antigens. Rheumatoid arthritis is an autoimmune disaese in which the person's immune system attacks the joints. This results in inflammation and thickening of the joint. In type I diabetes, immune system destroys insuling producing pancreatic cells resulting in little or no insulin production by the body. Inmultiple sclerosis, the immune system attacks the protective sheath (myelin) that covers nerve fibres and causes communication problems between brain and the spinal cord.Myasthenia gravisis a chronic autoimmune neuromuscular disease characterized by varying degrees of weakness of the skeletal (voluntary) muscles of the body. Addison's disease arises from problems with the adrenal gland such that not enough of the steroid hormonecortisoland possiblyaldosteroneare produced,most often due todamage by the body's own immune system.

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